BMC Endocr Disord. 2025 Apr 3;25(1):90. doi: 10.1186/s12902-025-01912-5.
ABSTRACT
BACKGROUND: Obesity is a major worldwide health problem and is associated with numerous diseases including diabetes, cardiovascular diseases, and some types of cancers. In the current cross-sectional study, we aimed to evaluate the association between a novel dietary obesity prevention score (DOPS) with metabolic parameters including serum lipid profile, glycemic markers, electrolyte status and blood pressure in individuals with obesity.
METHODS: Three hundred and four individuals with obesity aged 18-65 years old were recruited through convenient sampling; anthropometric and dietary assessments were performed and blood pressure was measured. Biochemical parameters including serum lipids, glycemic markers, some of liver function tests and electrolyte status were measured by standard laboratory methods.
RESULTS: Lower adiposity including lower body mass index (BMI) and fat mass and low systolic and diastolic blood pressures were observed at higher tertiles of versus lower tertiles of DOPS (P < 0.05). Also, lower low density lipoprotein cholesterol (LDL-c) and higher serum albumin concentrations were observed at higher tertiles of DOPS. There was no significant difference between other parameters across DOPS tertiles.
CONCLUSION: In our study, higher adherence to dietary obesity preventive score reduced obesity risk, blood pressure and serum LDL in individuals with obesity. Future longitudinal and interventional studies are needed to establish causal relationships.
CLINICAL TRIAL NUMBER: Not applicable.
PMID:40176013 | DOI:10.1186/s12902-025-01912-5