Humoral response 24 months after the first COVID-19 vaccination in people with HIV with and without diabetes

Scritto il 23/12/2024
da Louise Bering

AIDS. 2024 Dec 1;38(15):2100-2103. doi: 10.1097/QAD.0000000000004026. Epub 2024 Nov 14.

ABSTRACT

People with HIV (PWH) and people with diabetes mellitus have increased risk of severe COVID-19, but little is known about humoral response to COVID-19 vaccines in PWH with DM. We investigated SARS-CoV-2 antireceptor-binding domain (anti-RBD) immunoglobulin G (IgG) geometrical concentrations and neutralizing antibody capacity (nAB) in PWH with and without diabetes mellitus. Anti-RBD IgG and nAB in COVID-19-vaccinated PWH were not associated with diabetes mellitus-status or HbA1c 24 months after the initial COVID-19 vaccination.

PMID:39715497 | DOI:10.1097/QAD.0000000000004026