J Clin Med. 2025 Mar 19;14(6):2102. doi: 10.3390/jcm14062102.ABSTRACTBackground: Cardiorenal Syndrome (CRS) represents a growing global health challenge due to the increasing prevalence of coexisting kidney and heart disease. The complex pathophysiology of CRS demands an integrated, multidisciplinar
J Clin Med. 2025 Mar 19;14(6):2101. doi: 10.3390/jcm14062101.ABSTRACTKidney transplantation (KT) represents a pivotal intervention for patients with chronic kidney disease (CKD), significantly improving survival and quality of life. However, KT recipients face an array of non-immunological complicat
J Clin Med. 2025 Mar 19;14(6):2093. doi: 10.3390/jcm14062093.ABSTRACTBackground/Objectives: Diabetes mellitus is one of the most common chronic diseases worldwide. In addition to short-term and long-term complications, diabetes has a detrimental effect on the patients' mood. The main psychiatric dis
J Clin Med. 2025 Mar 18;14(6):2079. doi: 10.3390/jcm14062079.ABSTRACTBackground: Chronic Kidney Disease (CKD) affects 8-16% of the population worldwide and is characterized by an estimated Glomerular Filtration Rate (eGFR) of less than 60 mL/min/1.73 m2 for more than 3 months. The main purpose of th
J Clin Med. 2025 Mar 18;14(6):2065. doi: 10.3390/jcm14062065.ABSTRACTBackground/Objectives: Diabetic kidney disease (DKD) is a major cause of end-stage kidney disease and a leading contributor to morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). However, predictive models for
J Clin Med. 2025 Mar 15;14(6):1997. doi: 10.3390/jcm14061997.ABSTRACTGastroparesis, characterized by delayed gastric emptying without mechanical obstruction, is a recognized complication of long-standing diabetes. Its pathophysiology involves, amongst other mechanisms, autonomic dysfunction due to v
J Clin Med. 2025 Mar 14;14(6):1987. doi: 10.3390/jcm14061987.ABSTRACTPeripheral arterial disease (PAD) is a major complication in individuals with diabetes and is increasingly prevalent in those with diabetic foot ulcers (DFUs). Despite this, the characterisation of PAD in diabetic patients remains
J Clin Med. 2025 Mar 14;14(6):1978. doi: 10.3390/jcm14061978.ABSTRACTThe last two decades have proffered many remarkable choices in managing type 1 and type 2 diabetes mellitus. Leading the list are glucagon-like peptide-1 receptor agonists (GLP1RAs), the first of which, exenatide, was approved by t
J Clin Med. 2025 Mar 14;14(6):1960. doi: 10.3390/jcm14061960.ABSTRACTDiabetes mellitus has become a major public health problem due to aspects such as an alarming increase in prevalence, the morbidity and mortality associated with its complications and, not least, the economic burden. SGLT2 inhibito
J Clin Med. 2025 Mar 13;14(6):1934. doi: 10.3390/jcm14061934.ABSTRACTBackground: Acute heart failure (AHF) is one of the leading causes of admissions to the emergency department (ED). There is a need to develop an easy-to-use score that can be used in the ED to risk-stratify patients with AHF and in
J Clin Med. 2025 Mar 12;14(6):1918. doi: 10.3390/jcm14061918.ABSTRACTBackground: Carotid intima-media thickness (IMT) is a noninvasive surrogate marker of subclinical atherosclerosis and cardiovascular disease risk. This study explored IMT distribution across three carotid artery segments in a large
J Clin Med. 2025 Mar 12;14(6):1906. doi: 10.3390/jcm14061906.ABSTRACTAcromegaly is a chronic disease characterized by the excessive production of growth hormone (GH), resulting in elevated levels of insulin-like growth factor-1 (IGF-1). It is associated with a significantly increased risk of cardiov
J Clin Med. 2025 Mar 11;14(6):1883. doi: 10.3390/jcm14061883.ABSTRACTBackground: Diabetes mellitus is one of the greatest public health challenges worldwide and one of the major conditions contributing to a poorer quality of life. The main factors that may deteriorate quality of life among patients
J Clin Med. 2025 Mar 7;14(6):1809. doi: 10.3390/jcm14061809.ABSTRACTChronic obstructive pulmonary disease (COPD) and type 2 diabetes mellitus (T2DM) are highly prevalent chronic conditions, frequently coexisting due to their shared pathophysiological mechanisms and risk factors. Epidemiological stud
J Clin Med. 2025 Mar 7;14(6):1800. doi: 10.3390/jcm14061800.ABSTRACTBackground: Research on quality of life (QoL)-related concerns among patients with both diabetes mellitus (DM) and cancer is limited. This study compared the QoL-related concerns and characteristics among chemotherapy-treated patien
J Clin Med. 2025 Mar 7;14(6):1794. doi: 10.3390/jcm14061794.ABSTRACTBackground: Multiple daily injections (MDIs) have been a mainstay for insulin delivery by persons with type 1 diabetes mellitus (T1DM). "Smart" insulin pens (SIPs) offer several advantages over traditional insulin pens, such as a me
J Clin Med. 2025 Mar 7;14(6):1786. doi: 10.3390/jcm14061786.ABSTRACTBackground: Mental illnesses following an acute myocardial infarction (AMI) are a growing concern, as they are associated with worse outcomes for AMI patients. Our understanding of the prevalence of mental illnesses after an AMI is
J Clin Med. 2025 Mar 6;14(5):1770. doi: 10.3390/jcm14051770.ABSTRACTBackground/Objectives: An increase in body fat is linked to abnormalities in energy metabolism. We aimed at determining cardiometabolic risk in Algerian participants with obesity alone and with or without type 2 diabetes. The study
J Clin Med. 2025 Mar 5;14(5):1751. doi: 10.3390/jcm14051751.ABSTRACTBackground/Objectives: Kinesiophobia, or the fear of movement, is a significant problem in the rehabilitation of patients after a stroke, especially in individuals with diabetes, who have an increased risk of health complications. T
J Clin Med. 2025 Mar 4;14(5):1733. doi: 10.3390/jcm14051733.ABSTRACTBackground: Gastric cancer remains a leading global health challenge, despite advances in surgical techniques and perioperative care. Patients with gastric cancer present with a degree of postoperative complications, most notably an
J Clin Med. 2025 Feb 28;14(5):1664. doi: 10.3390/jcm14051664.ABSTRACTBackground/Objectives: The aim of this study was to investigate whether Gliatamin (choline alphoscerate), an acetylcholine precursor originally used to treat dementia, improves depressive symptoms in patients with type 2 diabetes.
J Clin Med. 2025 Feb 27;14(5):1625. doi: 10.3390/jcm14051625.ABSTRACTBackground/Objectives: Ankle-brachial index (ABI) is frequently measured in hemodialysis patients due to their high cardiovascular risk, while its potential role as a screening tool for assessing overall physical function and healt
J Clin Med. 2025 Feb 27;14(5):1631. doi: 10.3390/jcm14051631.ABSTRACTBackground/Objectives: Type 1 diabetes (T1D) is a chronic autoimmune condition characterized by the destruction of pancreatic β-cells, leading to insulin deficiency. Current therapies, such as islet transplantation, face significan
J Clin Med. 2025 Feb 27;14(5):1626. doi: 10.3390/jcm14051626.ABSTRACTIntroduction: Obesity is a rapidly growing common health problem worldwide that can lead to the development of gestational diabetes mellitus (GDM). However, GDM not only affects women with obesity but can also develop at any time,
