Haiyan Gu il 26/12/2024

Exploring the effect and mechanism of action of Jinlida granules (JLD) in the treatment of diabetes-associated cognitive impairment based on network pharmacology with experimental validation

Ann Med. 2025 Dec;57(1):2445181. doi: 10.1080/07853890.2024.2445181. Epub 2024 Dec 26.ABSTRACTOBJECTIVES: To explore the effect and the probable mechanisms of JLD in the treatment of type 2 diabetes mellitus (T2DM) - associated cognitive impairment (TDACI).METHODS: The effect of JLD in combating TDA

Naveenkumar Nallathambi il 26/12/2024

A study of SGLT2 inhibitors on levels of plasma atherogenesis biomarkers in diabetes

J Family Med Prim Care. 2024 Nov;13(11):5278-5281. doi: 10.4103/jfmpc.jfmpc_908_24. Epub 2024 Nov 18.ABSTRACTBACKGROUND: Diabetes, a chronic metabolic disorder with microvascular and macrovascular complications. Metabolites of hyperglycemia mediates endothelial injury resulting in cascade of atheros

Anish Chhillar il 25/12/2024

Hyaluronic Acid-Based Self-Healing Hydrogels for Diabetic Wound Healing

Adv Healthc Mater. 2024 Dec 25:e2404255. doi: 10.1002/adhm.202404255. Online ahead of print.ABSTRACTDiabetic wounds, particularly diabetic foot ulcers (DFUs), are significant threats to human well-being due to their impaired healing from poor circulation and high blood sugar, increased risk of infec

Jingwen Gao il 25/12/2024

Ghrelin alleviates inflammation and pyroptosis by inhibiting TNF-α /caspase-8/caspase-3/ GSDME signalling pathways in an in vitro model of high glucose induced liver injury

Tissue Cell. 2024 Dec 10;93:102672. doi: 10.1016/j.tice.2024.102672. Online ahead of print.ABSTRACTDiabetic liver injury (DLI) refers to liver injury resulting from prolonged chronic hyperglycemia and represents a significant complication associated with diabetes, The specific pathogenic mechanism o

Kenana Ljuca il 25/12/2024

Association of plasma endocan levels with metabolic parameters and predictive value of endocan for the development of complications in patients with type 2 diabetes mellitus: An observational study

Biomol Biomed. 2024 Dec 18. doi: 10.17305/bb.2024.11512. Online ahead of print.ABSTRACTThe aim of the current research was to investigate the association between plasma endocan levels and metabolic control parameters, as well as to evaluate its predictive value for clinical complications in patients

Guochen Li il 25/12/2024

Association between major depressive disorder or depressive symptoms and the risk of vascular complications among patients with type 2 diabetes, and the mediating role of metabolic biomarkers: an analysis of the UK Biobank cohort

EClinicalMedicine. 2024 Dec 6;79:102982. doi: 10.1016/j.eclinm.2024.102982. eCollection 2025 Jan.ABSTRACTBACKGROUND: Depression is a severe mental disorder commonly co-morbid with diabetes, but it remains to elucidate whether depression is associated with the risks of a wide range of vascular compli

Feras A Alghamdi il 25/12/2024

Bridging the Gap Between Diabetes and Cardiovascular Disease: A Comparative Review of Different Glucagon-Like Peptide-1 (GLP-1) Agonists: Efficacy, Safety, and Patient Outcomes

Cureus. 2024 Nov 24;16(11):e74345. doi: 10.7759/cureus.74345. eCollection 2024 Nov.ABSTRACTDiabetes mellitus, particularly Type 2 diabetes (T2DM) remains a significant concern globally with an increase in prevalence reported in recent years. If diabetes is not managed properly, it can lead to severa

Maulee Hiromi Arambewela il 25/12/2024

Young-Onset Diabetes in Sri Lanka: Experience From the Developing World

J Diabetes Res. 2024 Dec 17;2024:7557153. doi: 10.1155/jdr/7557153. eCollection 2024.ABSTRACTBackground: Young-onset diabetes (YOD) is characterised by unique diagnostic and management challenges more pronounced in resource-limited settings like Sri Lanka. Aims: We aimed to ascertain the prevalence,

Xiaopeng Jia il 25/12/2024

Application of extracellular vesicles in diabetic osteoporosis

Front Endocrinol (Lausanne). 2024 Dec 10;15:1466775. doi: 10.3389/fendo.2024.1466775. eCollection 2024.ABSTRACTAs the population ages, the occurrence of osteoporosis is becoming more common. Diabetes mellitus is one of the factors in the development of osteoporosis. Compared with the general populat