Adv Exp Med Biol. 2025 Apr 4. doi: 10.1007/5584_2025_859. Online ahead of print.ABSTRACTDiabetes mellitus, arising due to inadequate insulin release or insulin resistance, can be addressed through β-cell replacement therapy. Given the limited availability of islet cadaveric donors, alternative strat
Protoplasma. 2025 Apr 3. doi: 10.1007/s00709-025-02057-x. Online ahead of print.ABSTRACTDiabetes mellitus is a chronic condition marked by high blood glucose levels, resulting from either insufficient insulin production or poor insulin function. While conventional treatments have progressed, there i
Front Microbiol. 2025 Mar 19;16:1554189. doi: 10.3389/fmicb.2025.1554189. eCollection 2025.ABSTRACTThe gut microbiota is closely associated with the onset and development of type 2 diabetes mellitus (T2DM), characterized by insulin resistance (IR) and chronic low-grade inflammation. However, despite
Diabetes Metab Syndr Obes. 2025 Mar 29;18:941-954. doi: 10.2147/DMSO.S413623. eCollection 2025.ABSTRACTBACKGROUND: Insulin-induced lipohypertrophy (LH) is a common complication of insulin therapy. However, its ultrasound characteristics, classification, and progression patterns remain poorly underst
World J Radiol. 2025 Mar 28;17(3):100168. doi: 10.4329/wjr.v17.i3.100168.ABSTRACTBACKGROUND: Acromegaly is caused by a pituitary neuroendocrine tumor (PitNET) with excessive production of growth hormone (GH), leading to multisystem complications. Previous studies have identified predictors of diseas
Front Pharmacol. 2025 Mar 19;16:1568828. doi: 10.3389/fphar.2025.1568828. eCollection 2025.ABSTRACTThe present review explores the role of endogenous hormones, such as cortisol, melatonin, thyroid hormones, sex hormones, and insulin, in the modulation of the immune response to a human metapneumoviru
Front Immunol. 2025 Mar 19;16:1554941. doi: 10.3389/fimmu.2025.1554941. eCollection 2025.ABSTRACTAging leads to a decline in the mass and function of skeletal muscles, a condition known as sarcopenia. It was previously reported that aging-related alterations in protein degradation, chronic inflammat
Clin Ter. 2025 Mar-Apr;176(2):148-149. doi: 10.7417/CT.2025.5197.ABSTRACTBACKGROUND: Although metformin can cross the placenta, its utility in treating gestational diabetes mellitus (GDM) is still debatable.AIM: The purpose of this study was to assess how metformin and insulin affect the outcomes fo
Diabetes Obes Metab. 2025 Apr 2. doi: 10.1111/dom.16360. Online ahead of print.ABSTRACTAIMS: To estimate the relative treatment effect of iGlarLixi (a fixed-ratio combination of insulin glargine 100 U/mL plus lixisenatide) versus premixed insulin IDegAsp (insulin degludec plus insulin aspart) in peo
Cardiovasc Diabetol. 2025 Apr 2;24(1):148. doi: 10.1186/s12933-025-02710-y.ABSTRACTBACKGROUND AND AIMS: The hemoglobin glycation index (HGI) has been linked to cardiovascular disease in diabetic patients. However, it remains unclear whether an elevated HGI similarly affects the cardiovascular system
BMC Vet Res. 2025 Apr 2;21(1):237. doi: 10.1186/s12917-025-04702-2.ABSTRACTBACKGROUND: Glaesserella parasuis elicits severe inflammatory responses and vascular damage, thus resulting in high mortality and morbidity in pigs; consequently, early diagnosis and treatment are critical to controlling econ
Sci Rep. 2025 Apr 2;15(1):11232. doi: 10.1038/s41598-025-95055-1.ABSTRACTRetinopathy of prematurity (ROP) remains a leading cause of childhood blindness globally. The clinical progression of ROP exhibits notable similarities to infantile hemangioma (IH), suggesting shared risk factors and underlying
Transl Psychiatry. 2025 Apr 2;15(1):117. doi: 10.1038/s41398-025-03330-6.ABSTRACTElectroconvulsive therapy (ECT) is an effective and rapid neuromodulatory intervention for treatment-resistant major depressive disorders (MDD). However, the precise mechanisms underlying their efficacies remain unclear
Diabetes Res Clin Pract. 2025 Mar 31:112119. doi: 10.1016/j.diabres.2025.112119. Online ahead of print.ABSTRACTAIM: The STOP study is a proof-of-concept, aimed at evaluating the effectiveness and safety of IdegLira in deintensifying diabetes therapy in elderly insulin-treated persons with T2DM.METHO
Ann Endocrinol (Paris). 2025 Mar 31:101730. doi: 10.1016/j.ando.2025.101730. Online ahead of print.ABSTRACTCONTEXT: Lipodystrophy and extreme insulin resistance syndrome are rare diseases with severe metabolic complications. Reported epidemiological data are conflicting.OBJECTIVE: We aimed to evalua
Pharmacol Res. 2025 Mar 31:107719. doi: 10.1016/j.phrs.2025.107719. Online ahead of print.ABSTRACTBrain tumors are complex, heterogeneous malignancies, often associated with significant morbidity and mortality. Emerging evidence suggests the important role of metabolic syndrome, such as that observe
J Nutr Biochem. 2025 Mar 31:109912. doi: 10.1016/j.jnutbio.2025.109912. Online ahead of print.ABSTRACTObesity is characterized by an enlargement of white adipose tissue caused by caloric excess. The depot-specific adaptation of white adipose tissue in individuals resistant to obesity despite a high-
Cytokine. 2025 Apr 1;190:156933. doi: 10.1016/j.cyto.2025.156933. Online ahead of print.ABSTRACTTumor necrosis factor (TNF) is identified as a pro-inflammatory cytokine critical to the pathology of liver disease. In the carbohydrate metabolism, TNF has been demonstrated to impede the insulin signali
Neurol Ther. 2025 Apr 2. doi: 10.1007/s40120-025-00724-y. Online ahead of print.ABSTRACTINTRODUCTION: Glucagon-like peptide-1 (GLP-1) is an incretin hormone that modulates glucose metabolism and insulin secretion. Recent translational and clinical research has evaluated the effects of GLP-1 receptor
Eur J Orthop Surg Traumatol. 2025 Apr 2;35(1):143. doi: 10.1007/s00590-025-04214-7.ABSTRACTBACKGROUND: The primary objective of this study was to investigate the association between preoperative hypertension and postoperative complications following open reduction internal fixation of distal radius
Eur J Neurosci. 2025 Apr;61(7):e70067. doi: 10.1111/ejn.70067.ABSTRACTMultiple sclerosis (MS) is a progressive demyelinating disease of the CNS, characterized by inflammation, the formation of CNS plaques, and damage to the neuronal myelin sheath (Graphical abstract). Fibroblast growth factor 21 (FG
Am J Physiol Renal Physiol. 2025 Apr 2. doi: 10.1152/ajprenal.00173.2024. Online ahead of print.ABSTRACTIntroduction: The ability to predict progression to severe acute kidney injury (AKI) remains an unmet challenge. Contributing to the inability to predict the course of AKI is a void of understandi
Diabetes Obes Metab. 2025 Apr 2. doi: 10.1111/dom.16378. Online ahead of print.ABSTRACTAIMS: To compare the risk of new-onset hyperglycaemia between inpatients treated versus non-treated with systemic glucocorticoids and identify factors associated with glucocorticoid-induced hyperglycaemia (GIH).MA
No abstractDiabetes Obes Metab. 2025 Apr 2. doi: 10.1111/dom.16377. Online ahead of print.NO ABSTRACTPMID:40171895 | DOI:10.1111/dom.16377
