Ruijie Xie il 03/04/2025

Large-Scale Proteomics Improve Risk Prediction for Type 2 Diabetes

Diabetes Care. 2025 Apr 3:dc242478. doi: 10.2337/dc24-2478. Online ahead of print.ABSTRACTOBJECTIVE: This study evaluated the incremental predictive value of proteomic biomarkers in assessing 10-year type 2 diabetes risk when added to the clinical Cambridge Diabetes Risk Score (CDRS).RESEARCH DESIGN

Martina Faraldi il 03/04/2025

Recent advances in the role of miRNAs in bone disease

Curr Opin Endocrinol Diabetes Obes. 2025 Apr 4. doi: 10.1097/MED.0000000000000914. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: This review explores the potential of circulating miRNAs as diagnostic biomarkers for osteoporosis and bone associated disease, highlighting challenges in translating m

James D Chambers il 03/04/2025

Assessing variation in US payer coverage of anti-vascular endothelial growth factor therapies for the treatment of age-related macular degeneration, diabetic retinopathy, and diabetic macular edema

J Manag Care Spec Pharm. 2025 Apr 3:1-10. doi: 10.18553/jmcp.2025.24340. Online ahead of print.ABSTRACTBACKGROUND: Timely anti-vascular endothelial growth factor (anti-VEGF) therapy is recommended to preserve vision in age-related macular degeneration (AMD), diabetic retinopathy (DR), and diabetic m

Sanjam S Sawhney il 02/04/2025

Gut microbiome evolution from infancy to 8 years of age

Nat Med. 2025 Apr 2. doi: 10.1038/s41591-025-03610-0. Online ahead of print.ABSTRACTThe human gut microbiome is most dynamic in early life. Although sweeping changes in taxonomic architecture are well described, it remains unknown how, and to what extent, individual strains colonize and persist and

Borja Quiroga il 02/04/2025

Spanish Registry of Renal Patients: 2022 Report and evolutive analysis

Nefrologia (Engl Ed). 2025 Apr 1:S2013-2514(25)00040-9. doi: 10.1016/j.nefroe.2025.03.002. Online ahead of print.ABSTRACTINTRODUCTION: Chronic kidney disease (CKD) will be the second leading cause of death in Spain by 2100. The Spanish Renal Disease Registry (REER) records the incidence, prevalence

Kristoffer Grundtvig Skaarup il 02/04/2025

Rationale and Design of NUDGE-CKD: A Nationwide Randomized Factorial Trial of Electronic Nudges for Increasing Guideline-Directed Medical Therapy in Chronic Kidney Disease

Am Heart J. 2025 Mar 31:S0002-8703(25)00097-3. doi: 10.1016/j.ahj.2025.03.015. Online ahead of print.ABSTRACTRATIONALE: Treatment guidelines for chronic kidney disease (CKD) recommend sodium-glucose cotransporter 2 inhibitors (SGLT2i) as first-line treatment for a broad range of individuals with CKD