FASEB J. 2025 Apr 15;39(7):e70487. doi: 10.1096/fj.202403032R.ABSTRACTThis study investigates the therapeutic potential of proanthocyanidins (PAC) in addressing Type 2 diabetic osteoporosis (T2DOP) by activating the SIRT6/Nrf2/GPX4 signaling pathways. T2DOP is characterized by compromised bone struc
Neurol Sci. 2025 Apr 3. doi: 10.1007/s10072-025-08152-4. Online ahead of print.ABSTRACTBACKGROUND: Late-onset AD refers to the occurrence of AD after the age of 65. It is the primary cause of late-onset dementia. Studies indicate that persons diagnosed with diabetes are more susceptible to late-onse
J Neuroimmune Pharmacol. 2025 Apr 3;20(1):32. doi: 10.1007/s11481-025-10200-x.ABSTRACTDapagliflozin, an approved SGLT2 inhibitor, has been shown to have extra-glycemic effects like cardio-reno protection. However, the neuroprotective effects of SGLT2 inhibitors against diabetic neuropathy (DN) have
Chem Biodivers. 2025 Apr 3:e202500531. doi: 10.1002/cbdv.202500531. Online ahead of print.ABSTRACTCinnamomi Ramulus-Puerariae Lobatae Radix (CR-PLR) possesses antidiabetic macrovascular pathology pharmacological effects, but its pharmacological mechanism of action remains unclear. A total of 197 CR-
Chin Med J (Engl). 2025 Apr 3. doi: 10.1097/CM9.0000000000003477. Online ahead of print.ABSTRACTBACKGROUND: Alpha-glucosidase inhibitors or dipeptidyl peptidase-4 inhibitors are both hypoglycemia agents that specifically impact on postprandial hyperglycemia. We compared the effects of acarbose and s
J Clin Endocrinol Metab. 2025 Apr 3:dgaf215. doi: 10.1210/clinem/dgaf215. Online ahead of print.ABSTRACTBACKGROUND: Type 2 diabetes mellitus (T2DM) is a major driver of coronary atherosclerosis progression, yet its impact is highly heterogeneous. Insulin resistance contributes to a complex interplay
No abstractFront Endocrinol (Lausanne). 2025 Mar 19;16:1514969. doi: 10.3389/fendo.2025.1514969. eCollection 2025.NO ABSTRACTPMID:40177630 | PMC:PMC11961410 | DOI:10.3389/fendo.2025.1514969
J Vasc Surg Cases Innov Tech. 2025 Feb 19;11(3):101752. doi: 10.1016/j.jvscit.2025.101752. eCollection 2025 Jun.ABSTRACTCongenital vascular anomalies present significant diagnostic and therapeutic challenges in the scope of vascular surgery. We present a case of anomalous dual posterior tibial (PT)
Front Microbiol. 2025 Mar 19;16:1554189. doi: 10.3389/fmicb.2025.1554189. eCollection 2025.ABSTRACTThe gut microbiota is closely associated with the onset and development of type 2 diabetes mellitus (T2DM), characterized by insulin resistance (IR) and chronic low-grade inflammation. However, despite
J Obes. 2025 Mar 26;2025:3964619. doi: 10.1155/jobe/3964619. eCollection 2025.ABSTRACTBackground: Diabetic ketoacidosis (DKA) is a life-threatening complication commonly seen in Type 1 diabetes mellitus (T1DM) but also affects Type 2 diabetes mellitus (T2DM). Objectives: To compare the clinical pres
Front Public Health. 2025 Mar 19;13:1488923. doi: 10.3389/fpubh.2025.1488923. eCollection 2025.ABSTRACTBACKGROUND: This study aims to examine the combined effects of depressive symptoms (DS) and cardiovascular disease (CVD) on fall risk in patients with type 2 diabetes mellitus (T2DM), as well as ev
Curr Diabetes Rev. 2025 Feb 4. doi: 10.2174/0115733998336827250114071627. Online ahead of print.ABSTRACTThe composition of the diet has altered over the past few decades, with a significant increase in the consumption of dietary sugars, particularly fructose, which has risen more than tenfold. This
Clin Ter. 2025 Mar-Apr;176(2):201-206. doi: 10.7417/CT.2025.5206.ABSTRACTPURPOSE: Serum netrin levels have been implicated in diabetes and its complications, including diabetic foot syndrome. Netrin 1, a protein encoded by the Netrin gene, has been recognized for its role in various physiological pr
J Investig Med. 2025 Apr 2:10815589251335049. doi: 10.1177/10815589251335049. Online ahead of print.ABSTRACTThis trial evaluated the effects of insulin aspart (IAsp) combined with insulin detemir and metformin on islet function in newly diagnosed type 2 diabetes mellitus (T2DM).Newly diagnosed T2DM
Diabetol Metab Syndr. 2025 Apr 2;17(1):113. doi: 10.1186/s13098-025-01677-w.ABSTRACTBoth type 1 and type 2 diabetes mellitus (T1D and T2D) are associated with poor bone health and an increased risk of fracture in adults. However, there are limited data regarding the effects of diabetes on the growin
